BREAKTHROUGH DISCOVERY
Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells
In the previous post I have mentioned about the Breast cancer stem cells which are more tumorigenic than normal differentiated breast cancer cells. These stem cells are dangerous and controlling them is very important for cancer prevention. In a breakthrough discovery, Scientists from University of Michigan have identified compounds that can inhibit the breast cancer stem cells. Sulforaphane a compound found in broccoli/broccoli sprouts Sulforaphane inhibits breast CSCs and downregulates the Wnt/beta-catenin self-renewal pathway. These findings support the use of sulforaphane for the chemoprevention of breast cancer stem cells. Further clinical studies can result in a new drug for breast cancer.
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